ABSTRACT
Objective@#To compare the 10 years risk for ischemic cardiovascular disease among Han, Uygur, Kazak nationality residents of Xinjiang Uygur Autonomous Region.@*Methods@#From October 2007 to October 2010,14 618 adult (aged ≥35 years) Han (n=5 757),Uygur (n=4 767) and Kazak (n=4 094) residents were selected to join this study through the four-stage stratified cluster sampling method from 7 cities and regions of Xinjiang Uygur Autonomous Region. The 10 years risk for ischemic cardiovascular disease was calculated according to the 10 years ischemic cardiovascular disease risk assessment form modified with Chinese characteristics and compared among the residents of 3 nationalities.@*Results@#(1) There were significant differences in age, body mass index, systolic blood pressure, diastolic blood pressure,fasting blood glucose,triglycerides,total cholesterol,low-density lipoprotein,high-density lipoprotein cholesterol, smoking history, and drinking history among Han, Uygur, Kazak nationality population (all P< 0.001). (2) There were significant differences in 10 years risk for ischemic cardiovascular disease between different gender and age group including 35-39, 40-44, 45-49, 50-54, 55-59, and ≥60 years old between Han, Uygur, Kazak nationality population (all P<0.001). (3) There were significant differences in rates of 10%-20% and>20% of 10 years risk for ischemic cardiovascular disease between different gender in Han, Uygur, Kazak nationality population (P values were 0.013 and <0.001, respectively). There were no significant differences in rates of <5% and 5%-9% of 10 years risk for ischemic cardiovascular disease between different gender in Han,Uygur,Kazak nationality population (all P>0.05).(4) There were significant differences in detection rates of diabetes,hypertension,smoking,hypertriglyceridemia,and obesity in male and female Han,Uygur,Kazak nationality population with 10 years risk for ischemic cardiovascular disease ≥10% (P<0.01 or 0.05). Meanwhile,there was significant difference in detection rates of hypercholesteremia in male Han, Uygur, Kazak nationality adults(P<0.001). There were no significant differences in detection rates of elevated low density lipoprotein cholesterol and reduced high density lipoprotein cholesterol in male and female Han,Uygur,Kazak nationality adults (all P>0.05).@*Conclusion@#There are gender and age differences in the 10 years risk for ischemic cardiovascular disease in ≥35 years old Han,Uygur,Kazak nationality adults from Xinjiang Uygur Autonomous Region.
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the prevalence and distribution of chronic heart failure (CHF) in the aged population of Xinjiang.</p><p><b>METHODS</b>Four-stage random sampling method was employed in this cross-sectional study to analyze the prevalence, risk factors and combined cardiovascular diseases of heart failure among different ethnic groups in aged (≥60 years and over) population of Xinjiang. Sample of studied population was recruited from 6 different regions in Xinjiang, namely Urumqi, Karamay, Fukang, Turfan Basin, Hetian and Ili Kazakh Autonomous Prefectures.</p><p><b>RESULTS</b>3 858 participants were surveyed, with the response rate as 89.14% . The prevalence of CHF was 4.30% in this cohort, including 2.74% in Han, 5.25% in Uighur and 6.32% in Kazakh ethnic groups respectively. The prevalence rates of CHF in different ethnic groups were significant different, statistically (χ(2) = 22.62, P = 0.00). Prevalence in males was 5.50%, predominant in the CHF, with females as 3.13%, and the difference between genders was significant (χ(2) = 13.65, P = 0.00). The prevalence rates of CHF increased in proportion with aging and were 3.39%, 3.68%, 5.12% and 6.82% in the 60-64, 65-69, 70-74, 75 years and over age groups, respectively. The prevalence rates of different age groups showed significant differences (χ(2) = 13.29, P = 0.004), and increased with age. The prevalence of CHF presented a rising trend (χ(2) = 12.07, P = 0.001).</p><p><b>RESULTS</b>of this study showed that atrial fibrillation was an independent risk factor for CHF (OR = 5.20, 95%CI: 2.32-11.70 and OR = 5.54, 95% CI:3.83-8.02). The most common combined single cardiovascular disease appeared to be hypertension(50 cases, the constituent ratio was 30.12%), followed by coronary heart disease (12 cases, 7.23%).</p><p><b>CONCLUSION</b>The prevalence of heart failure in population over 60 years was high in Xinjiang, and there showed ethnic differences. Hypertension and coronary heart disease were the basic cardiovascular diseases combined with heart failure in the various ethnic groups in Xinjiang. To strengthen epidemiological study on those high risk populations related to chronic heart failure was important on the strategies of prevention and treatment to this health problem.</p>